SCREENING THE EFFECT OF WATER POLLUTION WITH SOME PESTICIDES ON THE IMMUNE RESPONSE IN OREOCHROMIS NILOTICUS (TILAPIA NILOTICA)FISH

Author

Department of Hygiene, Preventive Medicine & Feeding Faculty of Veterinary Medicine, Moshtohor zagazig University; Benha Branch

Abstract

Nine groups of Oreochromis niloticus fish each consisting of 50 fish were used to assess the effect of pesticides on immunological response in fish. Four groups were immunized with Staphylococcus aureus antigen plus complete  Freund's adjuvant. Four other groups were not immunized, but injected with the adjuvant. Fish in all groups were exposed to 1/10 of LC50 of the tested pesticides namely, lindane, dialdrin, diazinon and malathion. One group was exposed to distilled water treatment and served as controls. The results revealed that the mean total RBCs, WBCs counts, PCV, Hb, MCV, MCH, MCHC  values were lower in vaccinated groups than in control groups exposed to tested pesticides . total protein , globulin and serum enzymes ALAT , ASAT values Were lower in vaccinated than in controls. Phagocytosis and antibody titer were lower in vaccinated as compared to non-vaccinated groups.

Main Subjects