PARTIAL NUCLEOTIDE SEQUENCE OF THE G GLYCOPROTEIN OF RESPIRATORY SYNCYTIAL VIRUS ISOLATED FROM WILD BIGHORN SHEEP MAY PROVE THAT IT IS NEARLY IDENTICAL TO THAT OF OVINE RESPIRATORY SYNCYTIAL VIRUS OF DOMESTIC SHEEP

ELERAKY, N; KANIA, S; POTGIETER, L

doi:10.21608/vmjg.2005.384669

PARTIAL NUCLEOTIDE SEQUENCE OF THE G GLYCOPROTEIN OF RESPIRATORY SYNCYTIAL VIRUS ISOLATED FROM WILD BIGHORN SHEEP MAY PROVE THAT IT IS NEARLY IDENTICAL TO THAT OF OVINE RESPIRATORY SYNCYTIAL VIRUS OF DOMESTIC SHEEP

Document Type : Original Article

Authors

¹ Department of Microbiology, Faculty of Vet. Medicine, Kafr Elsheikh, Tanta Univ.,Egypt

² Department of Comparative Medicine,College of Veterinary Medicine,University of Tennessee, Knoxville, Tennessee, USA

10.21608/vmjg.2005.384669

Abstract

The G glycoprotein is the most variable gene among different strains of human and bovine respiratory syncytial viruses (RSV). One isolate of ovine RSV isolated from domestic sheep has been molecularly characterized before. In this study, partial nucleotide sequence (65%) of the G glycoprotein gene of RSV isolate of wild bighorn sheep and its predicted protein are reported. Very high level of identity at the nucleotide and amino acid levels between the two RSV isolates of domestic sheep and wild Bighorn sheep suggests that Bighorn sheep RSV may be considered as a member of the ovine RSV subgroup. This information will help in understanding RSV epidemiology and vaccine development in cattle and sheep.

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