EFFECT OF SOME PROBIOTIC STRAINS ON LIPID METABOLISM

 
In the present study, Fifteen selected probiotic strains of lactic acid bacteria as (lactobacillus, Streptococcus and Bifidobacterium spp) were ex   amined for their ability to remove cholesterol (T-Ch) and triglycerides (TG) from laboratory media during their growth. All selected strains could remove T-Ch and triglycerides (TG) on different media as MRS-THIO broth media GM-THIO growth media except 2 strains only. A combination between the probiotic strains used was carried out to select the proper mixture in removing lipids. Derived yoghurt from the best mixture was analysed for T-Ch and TG under the manufacture conditions proved the ability of chosen mixture in removing lipids. The study extended to evaluate, the effect of yoghurt manufactured by probiotic strains (1% starter ) on the lipid profile through experimental hyperlipidemic rats (rats fed on 1% cholesterol and 0.5% of cholic acid dissolved in 20% coco-nut oil ration for 45 days). The hyperlipidemic rats were subdivided into four groups; Gl, fed on ration free probiotics served as (-) ve control group, G2, 3, 4 fed on ration containing different groups of strains from probiotics, L.acidophillus N10, Str.cremoris F 99 and Bif.ther-bifidum99 (B group); L.acidophillus N10, L.bulgaricus N5 and Str.thermophillus S1 (H group) ; L.acidophillus N10, Str.cremoris F50, L.bulgaricus N5 and Biflongum K69 (E group). The data showed that all the tested groups have similar significant reduction in serum T-Ch, LDL-Ch and TG as well as significant increase in the level of HDL-Ch . All the tested yoghurt showed significant reduction in serum total fatty acids (TFA). The most reduction effection fatty acids were obtained by the group H which could restore the ratio of unsaturated fatty