MINIMAL INHIBITORY CONCENTRATIONS OF QUINOLONES GROUP TO SOME AVIAN MYCOPLASMAS

Document Type : Original Article

Author

Animal Health Research Institute, Dokki, Giza, Egypt.

Abstract

 
Quinolones group (Ciprofloxacin, Enrofloxacin and Norfloxacin) was found to have antimicrobial activity (using growth inhibition test) on Mycoplasma synoviae, M. pullorum and M. iowae, while M. gallisepticum strains (S6, R, PG31 and F strains), M. gallinaceum, M. galinarum and M. iners were less sensitive. All the examined strains were sensitive to Lincospectin. Streptomycin had less effect on M. synoviae, M. pullorum. M. gallinarum and M.iners, while M. gallisepticum strains, M.gallinaceum and M. iowae were resistant.
 
Minimum inhibitory concentrations (MICs) of Ciprofloxacin and Enrofloxacin were between 0.006 Ug/ml (sensitive) for all the tested strains. In the case of Norfloxacin, most of the examined Strains were sensitive (0.024-0.048 Ug/ml) except M. gallisepticum (S6, R and F strains) and M.iowae were less sensitive (0,097-0.39 Ug/ml). Streptomycin had less effect on most tested Strains (0.39-1.56 Ug/ml), while M. iowae was resistant.

Main Subjects