Efficacy and pharmacokinetics of kanamycin were Studied in P. fluorescens infected Clarias lazera (Nile catfish). The clinical sings of P.fluorescens infection started after 12-24 hours post intraperitoneal inoculation. Kanamycin was injected in a single dose (20 mg/kg b.wt.) in the infected group and another apparently healthy control group. Recovery percent reached 73.33 in the infected fish group after 48 hours® post antibiotic injection Kanamycin was rapidly absorbed after intraperitoneal injection and reached its highest concentration 9.87+0.00059 and 9.20+0.85 µg/ml four hours post injection in normal and infected fish groups, respectively. Kanamycin was rapidly absorbed in infected fish ( a = 0.2726 + 0.002h"! and ty < & = 2.69 + 0.16 min.) than in normal fish a= 0.20420.009h"! and ty, a= 3.4420.14 min.). Kanamycin was rapidly excreted in infected fish with ty 5 B= 5.63+0.3764 hrs than in normal fish with tp 5 B= 7.55+1988 hrs. The interval between doses was short in infected fish 44.28 hrs than in normal fish 55.85hrs.
M., A., A., Y., S., A. E., & M., N. (1996). EFFICACY AND PHARMACOKINETICS OF KANAMYCIN IN PSEUDOMONAS ELUORESCENS INFECTED CLARIAS LAZERA FISH. Veterinary Medical Journal (Giza), 44(2), 443-451. doi: 10.21608/vmjg.1996.376554
MLA
AMER M.; YONIS A.; ABD EL-AZIZ S.; NAGUIB M.. "EFFICACY AND PHARMACOKINETICS OF KANAMYCIN IN PSEUDOMONAS ELUORESCENS INFECTED CLARIAS LAZERA FISH", Veterinary Medical Journal (Giza), 44, 2, 1996, 443-451. doi: 10.21608/vmjg.1996.376554
HARVARD
M., A., A., Y., S., A. E., M., N. (1996). 'EFFICACY AND PHARMACOKINETICS OF KANAMYCIN IN PSEUDOMONAS ELUORESCENS INFECTED CLARIAS LAZERA FISH', Veterinary Medical Journal (Giza), 44(2), pp. 443-451. doi: 10.21608/vmjg.1996.376554
VANCOUVER
M., A., A., Y., S., A. E., M., N. EFFICACY AND PHARMACOKINETICS OF KANAMYCIN IN PSEUDOMONAS ELUORESCENS INFECTED CLARIAS LAZERA FISH. Veterinary Medical Journal (Giza), 1996; 44(2): 443-451. doi: 10.21608/vmjg.1996.376554
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