SEROLOGICAL STUDIES FOLLOWING VACCINATION WITH ATTENUATED RIFT VALLEY FEVER (RVF) VACCINE IN EGYPT

Document Type : Original Article

Authors

Agriculture Research Center, Serum and Vaccine Research Institute, Abbasia, Cairo, Egypt.

Abstract

A total of 1190 serum samples were collected from different species of animals including cattle, buffaloes and sheep for a period of 9 months post vaccination with attenuated RVF vaccine. A serum neutralization test (SNT) was conducted . using microtiter plates, BHK cells, the RVF neutralizing antibodies reached 91.9% in sheep, 75.6% in buffaloes and 75.3% in cattle. The result of SNT was confirmed by Indirect Immunofluorescent Assay (IFA) and gave the same result obtained with SNT. The ‘protective level of RVF antibodies (1:40 or higher) obtained from this study lasted for a period of 9 months post vaccination with attenuated RVF vaccine.

Main Subjects