BIOCHEMICAL AND HAEMATOLOGICAL ‘CHANGES IN TILAPIA NILOTICA (OREOCHROMIS NILOTICUS) EXPOSED TO COPPER

Author

Department of Forensic Medicine and Toxicology, Faculty of Veterinary Medicine, Cairo University.

Abstract

 
The effect of exposure to sublethal concentration of copper sulfate for 3 weeks was studied in Tilapia nilotica fish. Marked elevations were recorded in the activities of serum glutamic pyruvic transaminase (GPT), glutamic oxalacetic transaminase (GOT), lactate dehydrogenase (LDH) and alkaline phosphatase (ALP). Serum total protein was increased with hyperglycaemia, while cholesterol level was reduced. Copper induced polycythemia accompanied by blood haemoglobin (Hb) level, haematocrit (Hct) value, and mean corpuscular haemoglobin concentration (MCHC). In addition, leucopenia, lymphopenia and neutrophilia were observed. It was concluded that copper produces tissue damage, metabolic stress and malfunctions of the haematopoietic system in Tilapia nilotica.

Main Subjects