CLINICAL, HEMATOLOGICAL, BIOCHEMICAL, ARTERIAL BLOOD GAS ANALYSIS AND ACID BASE CHANGES ASSOCIATED WITH VENTILATION AND RESPIRATORY DISEASES IN GERMAN HYPOSHEPHERD DOGS.

SALEH, I; IBRAHIM, A

doi:10.21608/vmjg.2002.375328

CLINICAL, HEMATOLOGICAL, BIOCHEMICAL, ARTERIAL BLOOD GAS ANALYSIS AND ACID BASE CHANGES ASSOCIATED WITH VENTILATION AND RESPIRATORY DISEASES IN GERMAN HYPOSHEPHERD DOGS.

Document Type : Original Article

Authors

I SALEH ¹
A IBRAHIM ²

¹ Department of Internal Medicine and Infectious Diseases, Faculty Of Veterinary Medicine, Cairo University, Giza, Egypt, 12211

² Department of Clinical Pathology, Faculty Of Veterinary Medicine, Cairo University, Giza, Egypt, 12211

10.21608/vmjg.2002.375328

Abstract

A total number of 40 male German Shepherd dogs less than 3 years age were used in this study. Ten of them were apparently healthy and used as a control group (group I), 10 of them were sampled just after performing an exercise (400- meter race) served as fitness group (group II), 10 of them were examined after transportation for one hour in crowded van at hot weather (42°C) and direct sun light (group III), and 10 were dis- eased with different respiratory diseases (2 tonsillitis. 4 bronchopneumonia, 4 pneumonia) (group IV). Blood and serum samples were collected from each animal in all groups for hematological and biochemical examination. In addition, heparinized blood samples were collected from the femoral artery from each animal for determination of acid-base status, and blood gas analysis. Results revealed significant increase in the respiratory rate in both groups (II). (p>0.05) and IV (p > 0.01) groups, and in pulse rate in group IV (p>0.01). The erythrogram showed significant in- crease in hemoglobin (HB), hematocrit (PCV) and RBCs count in both groups (II) and (III) (P>0.05).The leukogram showed significant increase in WBCs and neutrophils counts in groups (II) (P> 0.05) and (IV) (P>0.01) with significant decrease (P>0.05) in lymphocytes. Significant decrease of blood pH was noted in groups (III) and (IV) (P>0.001), significant increase in PaO2 in groups (III) and (IV) (P < 0.01), decrease in PaCO2 in groups (III) (p>0.01) and (IV) (P>0.05), significant increase in A-a gradient in groups III and IV (P>0.01), significant increase of bicarbonate in group IV (P>0.01) in comparison to the control group (1). Serum sodium showed significant in- crease in groups II and III (P>0.001); and significant decrease in group IV (P>0.01). Serum potassium revealed significant increase in group II. III (P>0.001) and IV (P>0.01).

Main Subjects