EFFECT OF BOVINE VIRUS DIARRHOEA ON THE IMMUNE RESPONSE OF EGYPTIAN BUFFALO CALVES

Document Type : Original Article

Authors

Department of Microbiology, Faculty of Veterinary Medicine, Cairo University

Abstract

Five buffalo calves were experimentally infected with Singer strain of bovine viral diarrhea virus (BVDV). The hematological changes and immune response were investigated. Transient leukopenia followed by leukocytosis was records BVD viral infection induced immunosuppression which was demonstrated by monitoring phagocytic activity of periphery blood monocytes and rosette formation T-cells. The cell-mediated immune response was tested by the lymphocyte transformation test. Serum neutralization test was performed to determine the humoral response.

Main Subjects