SOME PHARMACODYNAMIC EFFECTS AND ANTIMICROBIAL ACTIVITY OF ESSENTIAL OILS OF CERTAIN PLANTS USED IN EGYPTIAN FOLK MEDICINE

Document Type : Original Article

Authors

1 Department of Pharmacology, Faculty of Veterinary Medicine, Cairo University, Giza, Egypt.

2 Department of Pharmacology, Faculty of Pharmacy, Kasr-El-Ainy, Cairo 11562, Egypt.

3 Department of Microbiology, Faculty of Veterinary Medicine, Zagazig University, Egypt.

Abstract

In this study ten essential oils were prepared from their respective natural sources namely:  Cimmamomum cassia barks (cassia). Curcuma sp. Rihzospes (curcuma), Elettaria cardamomum fruits (cardamom), Eugenia caryophyllus flower buds (clove), Origanum syriacum herb (zatar), Onizanem majoranum herb (sweet majoram). Piper nigrum fruits (black pepper), Rosmarinus Affiicinalis leaves (rosemary), Salvia triloba L. {muaryamiyah) and Zingiber officinalis rhizomes {ginger). Their percentage yields, specific and refractive indices were determined. The essential oils ginger and black pepper markedly stimulated the motility of rabbit's jejunum al concentrations more than 47.2 and 70 mg/ml respectively. While the other essential oils possessed intestinal antispasmodic effects on (slated rabbit's jejunum. All tested oils produced inhibitory effect on the uterus of the pregnant rat. Concerning the antimicrobial study, the Sensitivity, of nineteen microbes (six Gram positive and six Gram-negative bacteria, and seven fungi), to tested essential oils was investigated at different concentrations (10, 25,50, 100 and 200 mg/ml), cassia oil showed a pronounced antibacterial activity against all tested bacteria in vitro.

Main Subjects

Veterinary Medical Journal (Giza)
Volume 42, Issue 1
January 1994
Pages 263-270

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