PHYSIOLOGICAL EFFECTS AND HEALTH BENEFITS OF FEEDING OLIGOSACCHARIDES

Document Type : Original Article

Authors

1 Department of Basic Medical Sciences, Purdue University, West Lafayette, Indiana 47907, USA.

2 Department of Physiology. Faculty of Veterinary Medicine, Cairo University, Egypt.

3 Department of Clinical Sciences, Faculty of Veterinary Medicine, Jordan University of Science and “Technology, Irbid, Jordan.

4 Department of Animal Sciences, Purdue University, West Lafayette, Indiana 47907, USA.

Abstract

Oligosaccharides possess several functional properties that lend then useful ingredients in animal Feeds and human foods. They have been shown to Serve as an indirect energy source and maintain The integrity of gastrointestinal mucosa. Because Of their nutritional properties and physiological Effects on the digestive system, oligosaccharides Have been studied and were shown to stimulate Mineral absorption and to increase the levels of Hematocrit and hemoglobin concentration in the blood. Moreover, oligosaccharides have been Found to increase, in the gut, the beneficial bacteria (Bifidobacterium Spp.) that alter luminal pH Thus leading to inhibition of potential pathogens. Oligosaccharides are credited for stimulation of Immune responses and restoration of normal intestinal flora. The use of oligosaccharides in Poultry diets has resulted in improvement in Weight gain, feed efficiency and reduction in Salmonella colonization. In pet animals such as Dogs and cats, oligosaccharide supplementation In the diet was shown to improve digestibility of Protein and amino acids and contributed to reduction in gas production in the lower gut. Based on the available scientific information to Date, oligosaccharides have the ability to reduce the risk of human disease such as coronary heart Disease, diabetes mellitus, and colon cancer. Oligosaccharides feeding had resulted in a reduction in lipid, glucose, triglycerides, and cholesterol levels in blood. The mechanisms by Which oligosaccharides affect these blood metabolites and the practical implication of including them in the diet have been reviewed in this paper.

Main Subjects