THYMIC AND SPLENIC CHANGES DUE TO VIRAL HAEMORRHAGIC DISEASE IN RABBIT AND INFLUENCE OF EMERGENCY VACCINATION

Document Type : Original Article

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Abstract

Vaccination against viral haemorrhagic disease in Rabbits was tried. The inactivated vaccine was inoculated on different timings; simultaneously With the experimental infection, on appearance of Clinical signs and 2 days after the beginning of Signs. Vaccination during illness with viral haemorrhagic disease was able to stop mortalities and Shorten the disease course gaving 70%, 60% & 36% protection rate in simultaneously infected Vaccinated, vaccinated on appearance of signs And vaccinated rabbits two days after the beginning Of signs. Seroconversion of the vaccinated rabbits Was estimated and compared with the control group. Histopathological changes in thymus and Spleen of rabbits experimentally infected with haemorrhagic disease virus were recorded. Lymphoid organs/body weight ratios on different intervals from vaccination and/or infection of different groups were measured.

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Veterinary Medical Journal (Giza)
Volume 49, Issue 1
January 2001
Pages 71-81

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