The genotoxic potential of technical hostathion was studied in the in vivo mouse system. The test Parameters used were chromosomal aberrations Assay and mitotic index in bone marrow cells; and Meiotic chromosomal aberrations assay and Meiotic index in germinal cells. Three dose levels (2.8, 4.2 and 5.6 mg/kg. b.wt.) were used for 3 And 5 days subacute treatments after oral administrations. Chromosome aberrations were observed In bone marrow cells and in diakineses-metaphase I cells from the testes. The dose and time yield effects statistically analysed. The results demonstrated that hostathion induced a significant structural chromosomal damages in somatic and Germinal cells as well as peridiploidy of numerical aberrations in somatic cells which were dose- And time dependent at all dose levels. A dose dependent significant decrease was observed in Mitotic and meiotic indices of mice cells. It was Concluded that hostathion has genotoxic effects. Therefore, the use of this pesticide in our life Must be restricted.
FARAG, I., ABDEL AZIZ, K., ZAHER, M., & DARWISH, H. (2001). GENOTOXIC EFFECT OF HOSTATHION IN MICE. Veterinary Medical Journal (Giza), 49(1), 59-69. doi: 10.21608/vmjg.2001.371862
MLA
I FARAG; K ABDEL AZIZ; M ZAHER; H DARWISH. "GENOTOXIC EFFECT OF HOSTATHION IN MICE". Veterinary Medical Journal (Giza), 49, 1, 2001, 59-69. doi: 10.21608/vmjg.2001.371862
HARVARD
FARAG, I., ABDEL AZIZ, K., ZAHER, M., DARWISH, H. (2001). 'GENOTOXIC EFFECT OF HOSTATHION IN MICE', Veterinary Medical Journal (Giza), 49(1), pp. 59-69. doi: 10.21608/vmjg.2001.371862
VANCOUVER
FARAG, I., ABDEL AZIZ, K., ZAHER, M., DARWISH, H. GENOTOXIC EFFECT OF HOSTATHION IN MICE. Veterinary Medical Journal (Giza), 2001; 49(1): 59-69. doi: 10.21608/vmjg.2001.371862
', './data/vmjg/coversheet/cover_en.jpg'))
View on SCiNiTO