SEMEN CHARACTERISTICS, BLOOD CONSTITUENTS AND TESTICULAR PATHOLOGY IN BALADI BUCKS INJECTED WITH FLUNIXIN MEGLUMINE (FINADYNE®).

Document Type : Original Article

Authors

1 Department of Animal Reproduction and A.I... National Research Center, Cairo, Egypt

2 Department of Animal Reproduction and A.I... National Research Center, Cairo, Egypt.

Abstract

Finadyne is one of the most commonly used non- steroidal anti-inflammatory drugs (NSAID). It is used in farm animals for treatment of stressful conditions. The present study aimed to clarify the effect of Finadyne injection on semen characteris- tics, blood constituents and testicular pathology of Baladi bucks.
Nine Baladi bucks raised at the National Research Center farm were divided into two groups, experimental (n=5) and control (n=4) groups. Experimental bucks were injected intramuscularly with 2 mg / kg. live body weight Flunixin meglumine (FM) every 2 weeks up to 2 months, while the control bucks were injected similarly with saline. A single semen sample was collected weekly from each buck using A.V. and subjected for evaluation. Blood samples were collected before, one and 2 months after treatment and complete Blood picture was performed. Moreover, seminal and blood plasma were separated for determination of testosterone level (RIA), total proteins, glucose, lipids, calcium and inorganic phosphorus (colorometrically). Additional blood samples were collected at the end of the experiment every half an hour up to 6 hours for further testosterone evaluation. At the end of the experiment, bucks were subjected for open unilateral castration. The obtained testes were examined grossly and tissue samples were taken and processed for histopathological examination.
Results indicated that Baladi bucks injected with Finadyne showed inferior libido and semen characteristics as indicated by long reaction time, low production of alive sperm cells with high sperm abnormalities as compared to the control group. Injection of Finadyne did not significantly affect the haemogram except for increasing the pro- thrombin time at the end of the experiment. Tes-

Main Subjects