EVALUATION OF THE PROTECTIVE EFFICACY OF ANTICOCCIDIAL DRUGS AND VACCINE IN PREVENTION OF COCCIDIOSIS IN BATTEZ0041SWRY REARED CHICKENS

M, Amer; Abd EL-A, Kutkat; Ali, Manal; El-Bayomi, Kh; AminGirh, Zenab; I, Elmarakby

doi:10.21608/vmjg.2011.368339

EVALUATION OF THE PROTECTIVE EFFICACY OF ANTICOCCIDIAL DRUGS AND VACCINE IN PREVENTION OF COCCIDIOSIS IN BATTEZ0041SWRY REARED CHICKENS

Document Type : Original Article

Authors

¹ Poult. Dis. Depart., Facult.of Vet. Med., Cairo University

² Poult. Dis. Depart., NRC.

³ Poult. Dis. Depart., NRC

⁴ Vet. Military Service

10.21608/vmjg.2011.368339

Abstract

Efficacy of feed additive anticoccidial drugs (Salinomycin 60 ppm or diclazuril 200 g/ton) and live vaccine "Coccivac ®)" in prevention of experimental coccidiosis in battery reared reared chickens was conducted. Clinical signs and/or mortalities, weekly average body weight and feed Intake, feed conversion rate (FCR), challenge test, oocyst count, and lesion score were taken as criteria for evaluation. Salinomycin group showed FCR similar to diclazuril, while Vaccinated group showed lower rates than vaccinated medicated groups at the 3 weeks of life. Total FCR of Salinomycin and diclazuril were lower (2.4) than control negative (2.1) and diclazuril + vaccine (2.2) while vaccinated group and vaccinated Salinomycin medicated group are moderate in between. Vaccinated group and vaccinated medicated with Salinomycin showed lesions at all parts of the Intestine at 29 and 33 days postvaccination, while in vaccinated medicated with diclazuril,
lesions only in upper and middle part. Vaccinated non- medicated group 4 showed higher oocyst count/gm of drooping from the 4th day post vaccination (dpv) than vaccinated medicated groups 5 and 6. Birds received diclazuril and vaccine showed lower count than vaccine + Salinomycin group at all intervals. Following challenge, vaccinated groups showed no marked signs or mortalities while examined droppings revealed presence of oocyst in concentration of 180/gram of faces at 2 dpc, 7680/g. at 8 dpc and 1200/g, at 11 dpc. Oocyst count/g in both vaccinated and/or medicated challenged chickens was lower than negative control groups. Birds received only vaccine induced higher and earlier oocyst shedding than those were vaccinated and medicated. Our study pointed out that the use of coccidiostate in the ration of "Coccivac®) vaccinated floor reared chickens was of value in lowering of the vaccinal reaction, oocyst shedding and improve FCR; where re-infection with vaccinal oocyst it possible.

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