Oxidative Stress Biomarkers in Dermatophytosis Infected Dogs

Document Type : Original Article

Authors

Dept. of Medicine and Infectious Diseases, Faculty of Veterinary Medicine, Cairo University

Abstract

Skin affections especially of fungal etiology are common problem faced on daily basis in canine practice. This work aimed to investigate selected oxidative stress biomarkers in dermatophytosis infected dogs. Clinical studies were applied on 20 dog and for investigation of hematological, biochemical and _ oxidative stress biomarkers. Leukocytosis (p<0.0f) along with monocytopenia (p<0.05) and significant elevation in ALP(p<0.05) were the most recorded hemat- biochemical alterations. The oxidative stress biomarkers showed significant decrease in glutathione peroxidase (GPX)(p<0.05) and plasma zinc levels(p<0.05). Dermatophytes infection represents a stress factor to the animal affecting its antioxidant mechanism system.

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